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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DYNC2H1
All Species:
23.03
Human Site:
S475
Identified Species:
50.67
UniProt:
Q8NCM8
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NCM8
NP_001073932
4307
492594
S475
G
D
A
S
G
P
L
S
G
K
N
L
S
E
V
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_536596
4306
491933
S475
G
E
A
S
G
P
L
S
G
K
N
L
S
E
V
Cat
Felis silvestris
Mouse
Mus musculus
Q45VK7
4306
492321
S475
G
D
P
S
G
P
L
S
G
K
N
L
S
E
V
Rat
Rattus norvegicus
Q9JJ79
4306
492200
S475
G
D
A
S
G
P
L
S
G
K
N
L
S
E
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509757
4391
500194
S566
G
E
L
S
G
P
L
S
G
R
N
L
S
E
V
Chicken
Gallus gallus
XP_417173
4301
491979
S473
G
D
V
S
G
P
L
S
G
K
N
L
S
E
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P37276
4639
530166
A645
V
A
G
S
I
I
W
A
R
Q
I
D
N
Q
L
Honey Bee
Apis mellifera
XP_395108
4023
452032
L449
L
I
R
E
A
R
A
L
S
S
Q
G
V
E
L
Nematode Worm
Caenorhab. elegans
Q19542
4171
473799
S454
V
W
I
R
Q
Q
T
S
Q
M
E
S
I
R
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P36022
4092
471329
S460
T
I
K
S
I
S
P
S
T
Y
H
E
E
I
Q
Red Bread Mold
Neurospora crassa
P45443
4367
495560
Q662
S
E
A
H
A
M
A
Q
L
H
D
L
P
P
V
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
93.5
N.A.
93.3
93
N.A.
85.8
79.7
N.A.
N.A.
N.A.
26.4
30.3
40.7
N.A.
Protein Similarity:
100
N.A.
N.A.
96.5
N.A.
97.1
97
N.A.
91.8
89.4
N.A.
N.A.
N.A.
47.8
52.5
61.2
N.A.
P-Site Identity:
100
N.A.
N.A.
93.3
N.A.
93.3
100
N.A.
80
93.3
N.A.
N.A.
N.A.
6.6
6.6
6.6
N.A.
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
93.3
100
N.A.
93.3
93.3
N.A.
N.A.
N.A.
40
13.3
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23.8
27.6
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.3
48.2
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
20
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
37
0
19
0
19
10
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
37
0
0
0
0
0
0
0
0
10
10
0
0
0
% D
% Glu:
0
28
0
10
0
0
0
0
0
0
10
10
10
64
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
55
0
10
0
55
0
0
0
55
0
0
10
0
0
0
% G
% His:
0
0
0
10
0
0
0
0
0
10
10
0
0
0
0
% H
% Ile:
0
19
10
0
19
10
0
0
0
0
10
0
10
10
0
% I
% Lys:
0
0
10
0
0
0
0
0
0
46
0
0
0
0
0
% K
% Leu:
10
0
10
0
0
0
55
10
10
0
0
64
0
0
19
% L
% Met:
0
0
0
0
0
10
0
0
0
10
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
55
0
10
0
0
% N
% Pro:
0
0
10
0
0
55
10
0
0
0
0
0
10
10
0
% P
% Gln:
0
0
0
0
10
10
0
10
10
10
10
0
0
10
10
% Q
% Arg:
0
0
10
10
0
10
0
0
10
10
0
0
0
10
0
% R
% Ser:
10
0
0
73
0
10
0
73
10
10
0
10
55
0
10
% S
% Thr:
10
0
0
0
0
0
10
0
10
0
0
0
0
0
0
% T
% Val:
19
0
10
0
0
0
0
0
0
0
0
0
10
0
64
% V
% Trp:
0
10
0
0
0
0
10
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _